Neurotoxic Thioether Adducts of 3,4-Methylenedioxymethamphetamine Identified in Human Urine After Ecstasy Ingestion

3,4-Methylenedioxymethamphetamine (MDMA, Ecstasy) is a widely misused synthetic amphetamine derivative and a serotonergic neurotoxicant in animal models and possibly humans. The underlying mechanism of neurotoxicity involves the formation of reactive oxygen species although their source remains uncl...

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Main Authors: Perfetti, Ximena, O'Mathúna, Brian, Pizarro, Nieves, Cuyàs, Elisabet, Khymenets, Olha, Almeida, Bruno, Pellegrini, Manuela, Pichini, Simona, Lau, Serrine S., Monks, Terrence J., Farré, Magí, Pascual, Jose Antonio, Joglar, Jesús, de la Torre, Rafael
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Pharmacology and Experimental Therapeutics 2009
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2698942/
https://ncbi.nlm.nih.gov/pubmed/19349378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.108.026393
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