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Inhibition of complement activation, myeloperoxidase, NET formation and oxidant activity by PIC1 peptide variants

BACKGROUND: A product of rational molecular design, PA-dPEG24 is the lead derivative of the PIC1 family of peptides with multiple functional abilities including classical complement pathway inhibition, myeloperoxidase inhibition, NET inhibition and antioxidant activity. PA-dPEG24 is composed of a se...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Hair, Pamela S., Enos, Adrianne I., Krishna, Neel K., Cunnion, Kenji M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6938345/
https://ncbi.nlm.nih.gov/pubmed/31891617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0226875
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