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Inhibition of Myeloperoxidase Activity in Cystic Fibrosis Sputum by Peptide Inhibitor of Complement C1 (PIC1)

Myeloperoxidase is the major peroxidase enzyme in neutrophil granules and implicated in contributing to inflammatory lung damage in cystic fibrosis. Free myeloperoxidase is present in cystic fibrosis lung fluid and generates hypochlorous acid. Here we report a new inhibitor of myeloperoxidase activi...

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Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: Hair, Pamela S., Sass, Laura A., Krishna, Neel K., Cunnion, Kenji M.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5279725/
https://ncbi.nlm.nih.gov/pubmed/28135312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0170203
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