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Inhibition of Immune Complex Complement Activation and Neutrophil Extracellular Trap Formation by Peptide Inhibitor of Complement C1

Two major aspects of systemic lupus erythematosus (SLE) pathogenesis that have yet to be targeted therapeutically are immune complex-initiated complement activation and neutrophil extracellular trap (NET) formation by neutrophils. Here, we report in vitro testing of peptide inhibitor of complement C...

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Publié dans:Front Immunol
Auteurs principaux: Hair, Pamela S., Enos, Adrianne I., Krishna, Neel K., Cunnion, Kenji M.
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2018
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5879100/
https://ncbi.nlm.nih.gov/pubmed/29632531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00558
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