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Single Cell Proteome Mapping of Tissue Heterogeneity Using Microfluidic Nanodroplet Sample Processing and Ultrasensitive LC-MS

Biological tissues are highly heterogeneous, consisting of a variety of cell types, subpopulations, and substructures. Understanding heterogeneity at the single cell level is of great interest for biomedical research. While MS-based proteomic analyses are capable of quantifying thousands of proteins...

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Detalhes bibliográficos
Publicado no:J Biomol Tech
Main Authors: Kelly, Ryan, Zhu, Ying, Liang, Yiran, Cong, Yongzheng, Piehowski, Paul, Dou, Maowei, Zhao, Rui, Qian, Wei-Jun, Burnum-Johnson, Kristin, Ansong, Charles
Formato: Artigo
Idioma:Inglês
Publicado em: Association of Biomolecular Resource Facilities 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6938103/
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