Human leukocyte antigen (HLA) class II peptide flanking residues tune the immunogenicity of a human tumor-derived epitope

CD4(+) T-cells recognize peptide antigens, in the context of human leukocyte antigen (HLA) class II molecules (HLA-II), which through peptide-flanking residues (PFRs) can extend beyond the limits of the HLA binding. The role of the PFRs during antigen recognition is not fully understood; however, re...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:J Biol Chem
Hlavní autoři: MacLachlan, Bruce J., Dolton, Garry, Papakyriakou, Athanasios, Greenshields-Watson, Alexander, Mason, Georgina H., Schauenburg, Andrea, Besneux, Matthieu, Szomolay, Barbara, Elliott, Tim, Sewell, Andrew K., Gallimore, Awen, Rizkallah, Pierre, Cole, David K., Godkin, Andrew
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2019
Témata:
Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6937582/
https://ncbi.nlm.nih.gov/pubmed/31619516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.009437
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky