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The RNA-binding protein FMRP facilitates the nuclear export of N(6)-methyladenosine–containing mRNAs

N(6)-Methyladenosine (m(6)A) is the most abundant post-transcriptional mRNA modification in eukaryotes and exerts many of its effects on gene expression through reader proteins that bind specifically to m(6)A-containing transcripts. Fragile X mental retardation protein (FMRP), an RNA-binding protein...

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Vydáno v:J Biol Chem
Hlavní autoři: Hsu, Phillip J., Shi, Hailing, Zhu, Allen C., Lu, Zhike, Miller, Nimrod, Edens, Brittany M., Ma, Yongchao C., He, Chuan
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2019
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6937581/
https://ncbi.nlm.nih.gov/pubmed/31753916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.AC119.010078
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