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Inducible Exoc7/Exo70 knockout reveals a critical role of the exocyst in insulin-regulated GLUT4 exocytosis

Insulin promotes glucose uptake by triggering the translocation of glucose transporter type 4 (GLUT4) from intracellular vesicles to the plasma membrane through exocytosis. GLUT4 exocytosis is a vesicle fusion event involving fusion of GLUT4-containing vesicles with the plasma membrane. For GLUT4 ve...

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Vydáno v:J Biol Chem
Hlavní autoři: Wang, Shifeng, Crisman, Lauren, Miller, Jessica, Datta, Ishara, Gulbranson, Daniel R., Tian, Yuan, Yin, Qian, Yu, Haijia, Shen, Jingshi
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6937574/
https://ncbi.nlm.nih.gov/pubmed/31740584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.010821
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