The sensor kinase MtrB of Mycobacterium tuberculosis regulates hypoxic survival and establishment of infection

Paired two-component systems (TCSs), having a sensor kinase (SK) and a cognate response regulator (RR), enable the human pathogen Mycobacterium tuberculosis to respond to the external environment and to persist within its host. Here, we inactivated the SK gene of the TCS MtrAB, mtrB, generating the...

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Dettagli Bibliografici
Pubblicato in:J Biol Chem
Autori principali: Banerjee, Srijon Kaushik, Lata, Suruchi, Sharma, Arun Kumar, Bagchi, Shreya, Kumar, Manish, Sahu, Sanjaya Kumar, Sarkar, Debasree, Gupta, Pushpa, Jana, Kuladip, Gupta, Umesh Datta, Singh, Ramandeep, Saha, Sudipto, Basu, Joyoti, Kundu, Manikuntala
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2019
Soggetti:
Microbiology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6937564/
https://ncbi.nlm.nih.gov/pubmed/31653701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.009449
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