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MicroRNA 26a (miR-26a)/KLF4 and CREB-C/EBPβ regulate innate immune signaling, the polarization of macrophages and the trafficking of Mycobacterium tuberculosis to lysosomes during infection

For efficient clearance of Mycobacterium tuberculosis (Mtb), macrophages tilt towards M1 polarization leading to the activation of transcription factors associated with the production of antibacterial effector molecules such as nitric oxide (NO) and proinflammatory cytokines such as interleukin 1 β...

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التفاصيل البيبلوغرافية
الحاوية / القاعدة:	PLoS Pathog
المؤلفون الرئيسيون:	Sahu, Sanjaya Kumar, Kumar, Manish, Chakraborty, Sohini, Banerjee, Srijon Kaushik, Kumar, Ranjeet, Gupta, Pushpa, Jana, Kuladip, Gupta, Umesh D., Ghosh, Zhumur, Kundu, Manikuntala, Basu, Joyoti
التنسيق:	Artigo
اللغة:	Inglês
منشور في:	Public Library of Science 2017
الموضوعات:	Research Article
الوصول للمادة أونلاين:	https://ncbi.nlm.nih.gov/pmc/articles/PMC5466338/ https://ncbi.nlm.nih.gov/pubmed/28558034 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006410
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MicroRNA 26a (miR-26a)/KLF4 and CREB-C/EBPβ regulate innate immune signaling, the polarization of macrophages and the trafficking of Mycobacterium tuberculosis to lysosomes during infection

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