MicroRNA 26a (miR-26a)/KLF4 and CREB-C/EBPβ regulate innate immune signaling, the polarization of macrophages and the trafficking of Mycobacterium tuberculosis to lysosomes during infection

For efficient clearance of Mycobacterium tuberculosis (Mtb), macrophages tilt towards M1 polarization leading to the activation of transcription factors associated with the production of antibacterial effector molecules such as nitric oxide (NO) and proinflammatory cytokines such as interleukin 1 β...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Sahu, Sanjaya Kumar, Kumar, Manish, Chakraborty, Sohini, Banerjee, Srijon Kaushik, Kumar, Ranjeet, Gupta, Pushpa, Jana, Kuladip, Gupta, Umesh D., Ghosh, Zhumur, Kundu, Manikuntala, Basu, Joyoti
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5466338/
https://ncbi.nlm.nih.gov/pubmed/28558034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006410
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