MicroRNA 26a (miR-26a)/KLF4 and CREB-C/EBPβ regulate innate immune signaling, the polarization of macrophages and the trafficking of Mycobacterium tuberculosis to lysosomes during infection

For efficient clearance of Mycobacterium tuberculosis (Mtb), macrophages tilt towards M1 polarization leading to the activation of transcription factors associated with the production of antibacterial effector molecules such as nitric oxide (NO) and proinflammatory cytokines such as interleukin 1 β...

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Dades bibliogràfiques
Publicat a:PLoS Pathog
Autors principals: Sahu, Sanjaya Kumar, Kumar, Manish, Chakraborty, Sohini, Banerjee, Srijon Kaushik, Kumar, Ranjeet, Gupta, Pushpa, Jana, Kuladip, Gupta, Umesh D., Ghosh, Zhumur, Kundu, Manikuntala, Basu, Joyoti
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2017
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5466338/
https://ncbi.nlm.nih.gov/pubmed/28558034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006410
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