The sensor kinase MtrB of Mycobacterium tuberculosis regulates hypoxic survival and establishment of infection

Paired two-component systems (TCSs), having a sensor kinase (SK) and a cognate response regulator (RR), enable the human pathogen Mycobacterium tuberculosis to respond to the external environment and to persist within its host. Here, we inactivated the SK gene of the TCS MtrAB, mtrB, generating the...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Banerjee, Srijon Kaushik, Lata, Suruchi, Sharma, Arun Kumar, Bagchi, Shreya, Kumar, Manish, Sahu, Sanjaya Kumar, Sarkar, Debasree, Gupta, Pushpa, Jana, Kuladip, Gupta, Umesh Datta, Singh, Ramandeep, Saha, Sudipto, Basu, Joyoti, Kundu, Manikuntala
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2019
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6937564/
https://ncbi.nlm.nih.gov/pubmed/31653701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.009449
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