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Regulation of the autophagic PI3KC3 complex by laforin/malin E3-ubiquitin ligase, two proteins involved in Lafora disease

Lafora progressive myoclonus epilepsy is a fatal rare neurodegenerative disorder characterized by the accumulation of insoluble abnormal glycogen deposits in the brain and peripheral tissues. Mutations in at least two genes are responsible for the disease: EPM2A, encoding the glucan phosphatase lafo...

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Detalhes bibliográficos
Publicado no:Biochim Biophys Acta Mol Cell Res
Main Authors: Sanchez-Martin, Pablo, Lahuerta, Marcos, Viana, Rosa, Knecht, Erwin, Sanz, Pascual
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6937399/
https://ncbi.nlm.nih.gov/pubmed/31758957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2019.118613
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