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Revealing Polymorphic Phase Transformations in Polymer-Based Hot Melt Extrusion Processes

The inadvertent occurrence of polymorphic phase transformations in active pharmaceutical ingredients (APIs) during hot melt extrusion (HME) processes has been claimed to limit the application of this technique. Hence, the control of polymorphism would need to be addressed if there is any prospect of...

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Detalhes bibliográficos
Publicado no:Cryst Growth Des
Main Authors: Espinell, José R. Hernández, López-Mejías, Vilmalí, Stelzer, Torsten
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6936767/
https://ncbi.nlm.nih.gov/pubmed/31889927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.cgd.7b01374
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