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Novel Controlled Release Polymer-Lipid Formulations Processed by Hot Melt Extrusion

The aim of the study was to investigate the effect of novel polymer/lipid formulations on the dissolution rates of the water insoluble indomethacin (INM), co-processed by hot melt extrusion (HME). Formulations consisted of the hydrophilic hydroxypropyl methyl cellulose polymer (HPMCAS) and stearoyl...

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Detalhes bibliográficos
Publicado no:AAPS PharmSciTech
Main Authors: Maniruzzaman, Mohammed, Islam, Muhammad T., Halsey, Sheelagh, Amin, Devyani, Douroumis, Dennis
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4766126/
https://ncbi.nlm.nih.gov/pubmed/26689407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-015-0470-2
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