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Stabilization of hot-melt extrusion formulations containing solid solutions using polymer blends

This study was aimed at enhancing the physical stability of the drug clotrimazole (CT) and the polymer contained within hot-melt extrusion (HME) films using polymer blends of hydroxypropyl cellulose (HPC) and poly(ethylene oxide) (PEO). The HME films were investigated for solid-state characteristics...

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Main Authors: Prodduturi, Suneela, Urman, Kevin L., Otaigbe, Joshua U., Repka, Michael A.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Springer-Verlag 2007
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2750365/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/pt0802050
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