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Temporal and age-dependent effects of haptoglobin deletion on intracerebral hemorrhage-induced brain damage and neurobehavioral outcomes

Intracerebral hemorrhage (ICH) is a devastating stroke subtype and the presence of extracorpuscular hemoglobin (Hb) exacerbates brain damage. Haptoglobin (Hp) binds Hb, which prevents its oxidation and participation in neurotoxic reactions. Multiple studies have investigated the role of Hp under con...

詳細記述

保存先:
書誌詳細
出版年:Exp Neurol
主要な著者: Leclerc, Jenna L, Li, Chris, Jean, Stacy, Lampert, Andrew S, Amador, Claudia Loyola, Diller, Matthew A, Tolosano, Emanuela, Doré, Sylvain
フォーマット: Artigo
言語:Inglês
出版事項: 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6936604/
https://ncbi.nlm.nih.gov/pubmed/30790555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2019.01.011
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