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Genetic deletion of the PGE(2) EP3 receptor improves anatomical and functional outcomes after intracerebral hemorrhage

Intracerebral hemorrhage (ICH) is a stroke subtype associated with high mortality and morbidity. Following ICH, excitotoxicity and inflammation significantly contribute to secondary brain injury and poor outcomes. Prostaglandin E(2) (PGE(2)) levels rise locally with insult to the nervous system, and...

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Bibliografiske detaljer
Udgivet i:Eur J Neurosci
Main Authors: Leclerc, Jenna L, Lampert, Andrew S, Diller, Matthew A, Doré, Sylvain
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4696550/
https://ncbi.nlm.nih.gov/pubmed/25847406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ejn.12909
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