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Genetic deletion of the PGE(2) EP3 receptor improves anatomical and functional outcomes after intracerebral hemorrhage

Intracerebral hemorrhage (ICH) is a stroke subtype associated with high mortality and morbidity. Following ICH, excitotoxicity and inflammation significantly contribute to secondary brain injury and poor outcomes. Prostaglandin E(2) (PGE(2)) levels rise locally with insult to the nervous system, and...

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Detalhes bibliográficos
Publicado no:Eur J Neurosci
Main Authors: Leclerc, Jenna L, Lampert, Andrew S, Diller, Matthew A, Doré, Sylvain
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4696550/
https://ncbi.nlm.nih.gov/pubmed/25847406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ejn.12909
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