Deficiency of T cell CD40L has minor beneficial effects on obesity-induced metabolic dysfunction

OBJECTIVE: Obesity-associated metabolic dysfunction increases the risk of multiple diseases such as type 2 diabetes and cardiovascular disease. The importance of the co-stimulatory CD40-CD40L dyad in diet-induced obesity (DIO), with opposing phenotypes arising when either the receptor (aggravating)...

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Vydáno v:BMJ Open Diabetes Res Care
Hlavní autoři: Reiche, Myrthe E, den Toom, Myrthe, Willemsen, Lisa, van Os, Bram, Gijbels, Marion J J, Gerdes, Norbert, Aarts, Suzanne A B M, Lutgens, Esther
Médium: Artigo
Jazyk:Inglês
Vydáno: BMJ Publishing Group 2019
Témata:
Obesity Studies
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6936585/
https://ncbi.nlm.nih.gov/pubmed/31908798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjdrc-2019-000829
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