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PCA via joint graph Laplacian and sparse constraint: Identification of differentially expressed genes and sample clustering on gene expression data

BACKGROUND: In recent years, identification of differentially expressed genes and sample clustering have become hot topics in bioinformatics. Principal Component Analysis (PCA) is a widely used method in gene expression data. However, it has two limitations: first, the geometric structure hidden in...

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Bibliografski detalji
Izdano u:BMC Bioinformatics
Glavni autori: Feng, Chun-Mei, Xu, Yong, Hou, Mi-Xiao, Dai, Ling-Yun, Shang, Jun-Liang
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6936054/
https://ncbi.nlm.nih.gov/pubmed/31888433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-019-3229-z
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