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BAFF inhibition in SLE – is tolerance restored?

The B cell activating factor (BAFF) inhibitor, belimumab, is the first biologic drug approved for the treatment of SLE, and exhibits modest, but durable, efficacy in decreasing disease flares and organ damage. BAFF and its homolog APRIL are TNF-like cytokines that support the survival and differenti...

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Detalhes bibliográficos
Publicado no:Immunol Rev
Main Authors: Jackson, Shaun W, Davidson, Anne
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6935406/
https://ncbi.nlm.nih.gov/pubmed/31562657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imr.12810
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