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Generation of a Transgenic BALB/c Mouse Line with Selective Expression of Human Mesothelin in Thyroid Gland: Application in Mesothelin Targeted Immunotherapy
Despite encouraging clinical results with immune checkpoint inhibitors and other types of immunotherapies, the rate of failure is still very high. The development of proper animal models which could be applied to the screening of effective preclinical antitumor drugs targeting human tumor antigens,...
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| Vydáno v: | J Immunother |
|---|---|
| Hlavní autoři: | , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2019
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6935318/ https://ncbi.nlm.nih.gov/pubmed/30933045 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CJI.0000000000000263 |
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