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Generation of a Transgenic BALB/c Mouse Line with Selective Expression of Human Mesothelin in Thyroid Gland: Application in Mesothelin Targeted Immunotherapy

Despite encouraging clinical results with immune checkpoint inhibitors and other types of immunotherapies, the rate of failure is still very high. The development of proper animal models which could be applied to the screening of effective preclinical antitumor drugs targeting human tumor antigens,...

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Bibliografski detalji
Izdano u:J Immunother
Glavni autori: Bera, Tapan K., Liu, Wenlong, Leshem, Yasmin, King, Emily, Kozlov, Serguei, Pastan, Ira
Format: Artigo
Jezik:Inglês
Izdano: 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6935318/
https://ncbi.nlm.nih.gov/pubmed/30933045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CJI.0000000000000263
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