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A ligation-based single-stranded library preparation method to analyze cell-free DNA and synthetic oligos

BACKGROUND: Cell-free DNA (cfDNA), present in circulating blood plasma, contains information about prenatal health, organ transplant reception, and cancer presence and progression. Originally developed for the genomic analysis of highly degraded ancient DNA, single-stranded DNA (ssDNA) library prepa...

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Detalhes bibliográficos
Publicado no:BMC Genomics
Main Authors: Troll, Christopher J., Kapp, Joshua, Rao, Varsha, Harkins, Kelly M., Cole, Charles, Naughton, Colin, Morgan, Jessica M., Shapiro, Beth, Green, Richard E.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6935139/
https://ncbi.nlm.nih.gov/pubmed/31881841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-019-6355-0
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