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Deletion of SIRPα (signal regulatory protein-α) promotes phagocytic clearance of myelin debris in Wallerian degeneration, axon regeneration, and recovery from nerve injury

BACKGROUND: Recovery of function from traumatic nerve injury depends on the ability of severed axons to grow/regenerate back to their target tissues. This is achieved by successfully crossing the lesion site where physical impact severed axons, determined by the type of trauma, followed by successfu...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Neuroinflammation
Prif Awduron: Elberg, Gerard, Liraz-Zaltsman, Sigal, Reichert, Fanny, Matozaki, Takashi, Tal, Michael, Rotshenker, Shlomo
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6935070/
https://ncbi.nlm.nih.gov/pubmed/31883525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-019-1679-x
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