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Phagocytic receptors activate and immune inhibitory receptor SIRPα inhibits phagocytosis through paxillin and cofilin

The innate immune function of phagocytosis of apoptotic cells, tissue debris, pathogens, and cancer cells is essential for homeostasis, tissue repair, fighting infection, and combating malignancy. Phagocytosis is carried out in the central nervous system (CNS) by resident microglia and in both CNS a...

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Detalhes bibliográficos
Main Authors: Gitik, Miri, Kleinhaus, Rachel, Hadas, Smadar, Reichert, Fanny, Rotshenker, Shlomo
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3997012/
https://ncbi.nlm.nih.gov/pubmed/24795566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2014.00104
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