Structure-Guided Design of a Fluorescent Probe for the Visualization of FtsZ in Clinically Important Gram-Positive and Gram-Negative Bacterial Pathogens

Addressing the growing problem of antibiotic resistance requires the development of new drugs with novel antibacterial targets. FtsZ has been identified as an appealing new target for antibacterial agents. Here, we describe the structure-guided design of a new fluorescent probe (BOFP) in which a BOD...

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Pubblicato in:Sci Rep
Autori principali: Ferrer-González, Edgar, Fujita, Junso, Yoshizawa, Takuya, Nelson, Julia M., Pilch, Alyssa J., Hillman, Elani, Ozawa, Mayuki, Kuroda, Natsuko, Al-Tameemi, Hassan M., Boyd, Jeffrey M., LaVoie, Edmond J., Matsumura, Hiroyoshi, Pilch, Daniel S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6934700/
https://ncbi.nlm.nih.gov/pubmed/31882782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-56557-x
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