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Substituted 1,6-diphenylnaphthalenes as FtsZ-targeting antibacterial agents

Bacterial cell division occurs in conjunction with the formation of a cytokinetic Z-ring structure comprised of FtsZ subunits. Agents that disrupt Z-ring formation have the potential, through this unique mechanism, to be effective against several of the newly emerging multidrug-resistant strains of...

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Detalhes bibliográficos
Main Authors: Zhang, Yongzheng, Giurleo, Daniel, Parhi, Ajit, Kaul, Malvika, Pilch, Daniel S., LaVoie, Edmond J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3950478/
https://ncbi.nlm.nih.gov/pubmed/23481648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2013.02.016
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