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Combining the FtsZ-Targeting Prodrug TXA709 and the Cephalosporin Cefdinir Confers Synergy and Reduces the Frequency of Resistance in Methicillin-Resistant Staphylococcus aureus

Combination therapy of bacterial infections with synergistic drug partners offers distinct advantages over monotherapy. Among these advantages are (i) a reduction of the drug dose required for efficacy, (ii) a reduced potential for drug-induced toxicity, and (iii) a reduced potential for the emergen...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Kaul, Malvika, Mark, Lilly, Parhi, Ajit K., LaVoie, Edmond J., Pilch, Daniel S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4914665/
https://ncbi.nlm.nih.gov/pubmed/27161635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00613-16
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