C. elegans expressing D76N β(2)-microglobulin: a model for in vivo screening of drug candidates targeting amyloidosis

The availability of a genetic model organism with which to study key molecular events underlying amyloidogenesis is crucial for elucidating the mechanism of the disease and the exploration of new therapeutic avenues. The natural human variant of β(2)-microglobulin (D76N β(2)-m) is associated with a...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Faravelli, Giulia, Raimondi, Sara, Marchese, Loredana, Partridge, Frederick A., Soria, Cristina, Mangione, P. Patrizia, Canetti, Diana, Perni, Michele, Aprile, Francesco A., Zorzoli, Irene, Di Schiavi, Elia, Lomas, David A., Bellotti, Vittorio, Sattelle, David B., Giorgetti, Sofia
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2019
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6934621/
https://ncbi.nlm.nih.gov/pubmed/31882874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-56498-5
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares