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C. elegans expressing D76N β(2)-microglobulin: a model for in vivo screening of drug candidates targeting amyloidosis
The availability of a genetic model organism with which to study key molecular events underlying amyloidogenesis is crucial for elucidating the mechanism of the disease and the exploration of new therapeutic avenues. The natural human variant of β(2)-microglobulin (D76N β(2)-m) is associated with a...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6934621/ https://ncbi.nlm.nih.gov/pubmed/31882874 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-56498-5 |
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