Differential skewing of donor-unrestricted and γδ T cell repertoires in tuberculosis-infected human lungs

Unconventional T cells that recognize mycobacterial antigens are of great interest as potential vaccine targets against tuberculosis (TB). This includes donor-unrestricted T cells (DURTs), such as mucosa-associated invariant T cells (MAITs), CD1-restricted T cells, and γδ T cells. We exploited the d...

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Pubblicato in:J Clin Invest
Autori principali: Ogongo, Paul, Steyn, Adrie J.C., Karim, Farina, Dullabh, Kaylesh J., Awala, Ismael, Madansein, Rajhmun, Leslie, Alasdair, Behar, Samuel M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2019
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6934215/
https://ncbi.nlm.nih.gov/pubmed/31763997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI130711
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