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Myelin-specific CD8(+) T cells exacerbate brain inflammation in CNS autoimmunity
Multiple sclerosis (MS) is an inflammatory, demyelinating disease of the CNS. Although CD4(+) T cells are implicated in MS pathogenesis and have been the main focus of MS research using the animal model experimental autoimmune encephalomyelitis (EAE), substantial evidence from patients with MS point...
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| Publicado no: | J Clin Invest |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6934187/ https://ncbi.nlm.nih.gov/pubmed/31573979 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI132531 |
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