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Relapsing-remitting CNS autoimmunity mediated by GFAP-specific CD8 T cells

Multiple Sclerosis (MS) is an inflammatory disease of the CNS that causes the demyelination of nerve cells and destroys oligodendrocytes, neurons and axons. Historically, MS has been thought to be a CD4 T cell-mediated autoimmune disease of CNS white matter. However, recent studies have identified C...

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Detalhes bibliográficos
Main Authors: Sasaki, Katsuhiro, Bean, Angela, Shah, Shivanee, Schutten, Elizabeth, Huseby, Priya G., Peters, Bjorn, Shen, Zu T., Vanguri, Vijay, Liggitt, Denny, Huseby, Eric S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3967518/
https://ncbi.nlm.nih.gov/pubmed/24591371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1302911
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