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Immune Checkpoints in CNS Autoimmunity

A number of autoimmune diseases, including multiple sclerosis, are mediated by self-reactive T cells that have escaped the deletional mechanisms of central tolerance. Usually, these T cells are kept at bay through peripheral tolerance mechanisms including regulation through coinhibitory receptors an...

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Detalles Bibliográficos
Autores principales: Joller, Nicole, Peters, Anneli, Anderson, Ana C., Kuchroo, Vijay K.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3674871/
https://ncbi.nlm.nih.gov/pubmed/22725958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-065X.2012.01136.x
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