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A Pathogenic Role for Myelin-Specific Cd8(+) T Cells in a Model for Multiple Sclerosis

Multiple sclerosis (MS) is a demyelinating disease of the central nervous system (CNS) characterized by plaques of infiltrating CD4(+) and CD8(+) T cells. Studies of MS and experimental autoimmune encephalomyelitis (EAE), an animal model of MS, focus on the contribution of CD4(+) myelin-specific T c...

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Detalhes bibliográficos
Main Authors: Huseby, Eric S., Liggitt, Denny, Brabb, Thea, Schnabel, Bryan, Öhlén, Claes, Goverman, Joan
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2195947/
https://ncbi.nlm.nih.gov/pubmed/11535634
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