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Modulation of p53 Transactivation Domain Conformations by Ligand Binding and Cancer-Associated Mutations
Intrinsically disordered proteins (IDPs) are important functional proteins, and their deregulation are linked to numerous human diseases including cancers. Understanding how disease-associated mutations or drug molecules can perturb the sequence-disordered ensemble-function-disease relationship of I...
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| Publicado no: | Pac Symp Biocomput |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6934143/ https://ncbi.nlm.nih.gov/pubmed/31797597 |
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