Genetic Modification of CD8(+) T Cells to Express EGFR: Potential Application for Adoptive T Cell Therapies

Adoptive immunotherapy with ex vivo-expanded tumor-infiltrating lymphocytes (TILs) has achieved objective clinical responses in a significant number of patients with cancer. The failure of many patients to develop long-term tumor control may be, in part, due to exhaustion of transferred T cells in t...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Front Immunol
Hauptverfasser: Lozano, Teresa, Chocarro, Silvia, Martin, Celia, Lasarte-Cia, Aritz, del Valle, Cynthia, Gorraiz, Marta, Sarrión, Patricia, Ruiz de Galarreta, Marina, Lujambio, Amaia, Hervás-Stubbs, Sandra, Sarobe, Pablo, Casares, Noelia, Lasarte, Juan J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2019
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6934060/
https://ncbi.nlm.nih.gov/pubmed/31921216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.02990
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge