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A Time-Embedding Network Models the Ontogeny of 23 Hepatic Drug Metabolizing Enzymes

Pediatric patients are at elevated risk of adverse drug reactions, and there is insufficient information on drug safety in children. Complicating risk assessment in children, there are numerous age-dependent changes in the absorption, distribution, metabolism, and elimination of drugs. A key contrib...

詳細記述

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書誌詳細
出版年:Chem Res Toxicol
主要な著者: Matlock, Matthew K., Tambe, Abhik, Elliott-Higgins, Jack, Hines, Ronald N., Miller, Grover P., Swamidass, S. Joshua
フォーマット: Artigo
言語:Inglês
出版事項: 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6933754/
https://ncbi.nlm.nih.gov/pubmed/31304741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.chemrestox.9b00223
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