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ROR2 induces cell apoptosis via activating IRE1α/JNK/CHOP pathway in high-grade serous ovarian carcinoma in vitro and in vivo

BACKGROUND: Epithelial ovarian cancer (EOC) is the most lethal cancer in female genital tumors. New disease markers and novel therapeutic strategies are urgent to identify considering the current status of treatment. Receptor tyrosine kinases family plays critical roles in embryo development and dis...

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Pubblicato in:J Transl Med
Autori principali: Li, Rui, Liu, Tianfeng, Shi, Juanjuan, Luan, Wenqing, Wei, Xuan, Yu, Jiangtao, Mao, Hongluan, Liu, Peishu
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6933631/
https://ncbi.nlm.nih.gov/pubmed/31878941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-019-02178-x
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