Akt/mTOR-Mediated Autophagy Confers Resistance To BET Inhibitor JQ1 In Ovarian Cancer

BACKGROUND: Bromodomain and extra-terminal domain inhibitors like JQ1 have proved to be promising epigenetic agents for the treatment of malignant ovarian carcinoma. However, the resistance of ovarian cancer cells to BET inhibitors has not been elucidated. In this study, we investigated the potentia...

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書目詳細資料
發表在:Onco Targets Ther
Main Authors: Luan, Wenqing, Pang, Yingxin, Li, Rui, Wei, Xuan, Jiao, Xiaoxiao, Shi, Juanjuan, Yu, Jiangtao, Mao, Hongluan, Liu, Peishu
格式: Artigo
語言:Inglês
出版: Dove 2019
主題:
Original Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6781612/
https://ncbi.nlm.nih.gov/pubmed/31632060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S220267
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