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ROR2 induces cell apoptosis via activating IRE1α/JNK/CHOP pathway in high-grade serous ovarian carcinoma in vitro and in vivo

BACKGROUND: Epithelial ovarian cancer (EOC) is the most lethal cancer in female genital tumors. New disease markers and novel therapeutic strategies are urgent to identify considering the current status of treatment. Receptor tyrosine kinases family plays critical roles in embryo development and dis...

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Detalles Bibliográficos
Publicado en:J Transl Med
Main Authors: Li, Rui, Liu, Tianfeng, Shi, Juanjuan, Luan, Wenqing, Wei, Xuan, Yu, Jiangtao, Mao, Hongluan, Liu, Peishu
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6933631/
https://ncbi.nlm.nih.gov/pubmed/31878941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-019-02178-x
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