α‐Mangostin suppresses the de novo lipogenesis and enhances the chemotherapeutic response to gemcitabine in gallbladder carcinoma cells via targeting the AMPK/SREBP1 cascades

High rates of de novo lipid synthesis have been discovered in certain kinds of tumours, including gallbladder cancer (GBC). Unlike several other tumours, GBC is highly insensitive to standard adjuvant therapy, which makes its treatment even more challenging. Although several potential targets and si...

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Vydáno v:J Cell Mol Med
Hlavní autoři: Shi, Yu, Fan, Yangwei, Hu, Yuan, Jing, Jiayu, Wang, Chuying, Wu, Yinying, Geng, Qianqian, Dong, Xuyuan, Li, Enxiao, Dong, Danfeng
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2019
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Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6933365/
https://ncbi.nlm.nih.gov/pubmed/31762191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14785
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