α‐Mangostin suppresses the de novo lipogenesis and enhances the chemotherapeutic response to gemcitabine in gallbladder carcinoma cells via targeting the AMPK/SREBP1 cascades

High rates of de novo lipid synthesis have been discovered in certain kinds of tumours, including gallbladder cancer (GBC). Unlike several other tumours, GBC is highly insensitive to standard adjuvant therapy, which makes its treatment even more challenging. Although several potential targets and si...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Cell Mol Med
Prif Awduron: Shi, Yu, Fan, Yangwei, Hu, Yuan, Jing, Jiayu, Wang, Chuying, Wu, Yinying, Geng, Qianqian, Dong, Xuyuan, Li, Enxiao, Dong, Danfeng
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2019
Pynciau:
Original Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6933365/
https://ncbi.nlm.nih.gov/pubmed/31762191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14785
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