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α‐Mangostin suppresses the de novo lipogenesis and enhances the chemotherapeutic response to gemcitabine in gallbladder carcinoma cells via targeting the AMPK/SREBP1 cascades

High rates of de novo lipid synthesis have been discovered in certain kinds of tumours, including gallbladder cancer (GBC). Unlike several other tumours, GBC is highly insensitive to standard adjuvant therapy, which makes its treatment even more challenging. Although several potential targets and si...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Shi, Yu, Fan, Yangwei, Hu, Yuan, Jing, Jiayu, Wang, Chuying, Wu, Yinying, Geng, Qianqian, Dong, Xuyuan, Li, Enxiao, Dong, Danfeng
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6933365/
https://ncbi.nlm.nih.gov/pubmed/31762191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14785
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