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Artesunate inhibits the mevalonate pathway and promotes glioma cell senescence

Glioma is a common brain malignancy for which new drug development is urgently needed because of radiotherapy and drug resistance. Recent studies have demonstrated that artemisinin (ARS) compounds can display antiglioma activity, but the mechanisms are poorly understood. Using cell lines and mouse m...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Cell Mol Med
Hauptverfasser: Wei, Shupei, Liu, Lili, Chen, Zhiyu, Yin, Wenli, Liu, Yingzi, Ouyang, Qianying, Zeng, Feiyue, Nie, Yingjie, Chen, Tao
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6933330/
https://ncbi.nlm.nih.gov/pubmed/31746143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14717
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