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Senescence from glioma stem cell differentiation promotes tumor growth

Glioblastoma (GBM) is a lethal brain tumor composed of heterogeneous cellular populations including glioma stem cells (GSCs) and differentiated non-stem glioma cells (NSGCs). While GSCs are involved in tumor initiation and propagation, NSGCs’ role remains elusive. Here, we demonstrate that NSGCs und...

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Detalles Bibliográficos
Publicado en:Biochem Biophys Res Commun
Main Authors: Ouchi, Rie, Okabe, Sachiko, Migita, Toshiro, Nakano, Ichiro, Seimiya, Hiroyuki
Formato: Artigo
Idioma:Inglês
Publicado: 2016
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5176357/
https://ncbi.nlm.nih.gov/pubmed/26775840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2016.01.071
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