Artesunate inhibits the mevalonate pathway and promotes glioma cell senescence

Glioma is a common brain malignancy for which new drug development is urgently needed because of radiotherapy and drug resistance. Recent studies have demonstrated that artemisinin (ARS) compounds can display antiglioma activity, but the mechanisms are poorly understood. Using cell lines and mouse m...

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Foilsithe in:J Cell Mol Med
Main Authors: Wei, Shupei, Liu, Lili, Chen, Zhiyu, Yin, Wenli, Liu, Yingzi, Ouyang, Qianying, Zeng, Feiyue, Nie, Yingjie, Chen, Tao
Formáid: Artigo
Teanga:Inglês
Foilsithe: John Wiley and Sons Inc. 2019
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Original Articles
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6933330/
https://ncbi.nlm.nih.gov/pubmed/31746143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14717
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