Array comparative genomic hybridization based identification of key genetic alterations at 2p21-p16.3 (MSH2, MSH6, EPCAM), 3p23-p14.2 (MLH1), 7p22.1 (PMS2) and 1p34.1-p33 (MUTYH) regions in hereditary non polyposis colorectal cancer (Lynch syndrome) in the Kingdom of Saudi Arabia

Lynch syndrome is inherited in an autosomal dominant mode. Lynch syndrome is caused by impairment of one or more of the various genes (most frequently MLH1 and MSH2) involved in mismatch repair. In this study, whole genome comparative genomic hybridization array (array CGH) based genomic analysis wa...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Saudi J Biol Sci
Egile Nagusiak: Rasool, Mahmood, Pushparaj, Peter Natesan, Mirza, Zeenat, Imran Naseer, Muhammad, Abusamra, Heba, Alquaiti, Maha, Shaabad, Manal, Sibiany, Abdulrahman Mohamed Saeed, Gauthaman, Kalamegam, Al-Qahtani, Mohammed Hussein, Karim, Sajjad
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Elsevier 2020
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6933242/
https://ncbi.nlm.nih.gov/pubmed/31889830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sjbs.2019.06.012
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