Wnt Signaling Separates the Progenitor and Endocrine Compartments during Pancreas Development

In vitro differentiation of pluripotent cells into β cells is a promising alternative to cadaveric-islet transplantation as a cure for type 1 diabetes (T1D). During the directed differentiation of human embryonic stem cells (hESCS) by exogenous factors, numerous genes that affect the differentiation...

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Publicat a:Cell Rep
Autors principals: Sharon, Nadav, Vanderhooft, Jordan, Straubhaar, Juerg, Mueller, Jonas, Chawla, Raghav, Zhou, Quan, Engquist, Elise N., Trapnell, Cole, Gifford, David K., Melton, Douglas A.
Format: Artigo
Idioma:Inglês
Publicat: 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6933053/
https://ncbi.nlm.nih.gov/pubmed/31116975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.04.083
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