Genomic landscapes by multiregion sequencing combined with circulation tumor DNA detection contribute to molecular diagnosis in glioblastomas

Glioblastoma is a highly aggressive brain malignancy with a poor prognosis. Its high intratumor heterogeneity contributes to therapeutic resistance, tumor progression and recurrence. We sequenced 31 loci in 11 patients with glioblastoma (including one patient with samples available from the primary...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Yang, Chao, Tan, Yanli, Li, Shouwei, Zhou, Junhu, Wang, Qixue, Wang, Yunfei, Xie, Yingbin, Chen, Luyue, Li, Jie, Fang, Chuan, Kang, Chunsheng
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals 2019
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6932900/
https://ncbi.nlm.nih.gov/pubmed/31822636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.102526
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